Don’t request the determination of serum biomarkers like CEA, CA-125, HE4, CA-15.3, -fetoprotein or CA-19.9 for the diagnosis of neoplastic disease in asymptomatic patients.
The diagnostic sensitivity and specificity of these biomarkers are not sufficient to allow their use (diagnosis, screening, case-finding) in a population with a low prevalence of neoplastic diseases. Their use is recommended for the monitoring of the neoplasms that...
Don’t routinely request preoperative laboratory tests in low-risk patients (for minor surgery and for intermediate surgery in ASA 1, ASA 2 patients).
Hematological and biochemical preoperative tests don’t add significant elements to the clinical risk evaluation for minor or intermediate surgery in low-risk patient.
Don’t request serum protein electrophoresis nor search urinary Bence-Jones protein as laboratory test before contrast media administration.
The only real drawback for the administration of contrast media is renal insufficiency. It can be diagnosed measuring serum Creatinine (increased) and calculating the glomerular filtration rate (eGFR).
Don’t routinely request creatin kinase-MB (CK-MB), total creatin kinase (CK), aspartato transaminase (AST), lactic-dehydrogenase (LDH) e myoglobin diagnosing Acute Coronary Syndromes (ACS).
The cardio-specific troponins (cTn) are considered the markers of choice for the diagnosis of Myocardial Infarction (MI) and Acute Coronary Syndromes (ACS) on the basis of their specificity, sensitivity (both analytical and clinical) and negative predictive value...The campaign DOING MORE DOES NOT MEAN DOING BETTER – CHOOSING WISELY ITALY is promoted by Italy’s Slow Medicine
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