Don’t request serum protein electrophoresis nor search urinary Bence-Jones protein as laboratory test before contrast media administration.

Type of practice

Laboratory tests

The only real drawback for the administration of contrast media is renal insufficiency. It can be diagnosed measuring serum Creatinine (increased) and calculating the glomerular filtration rate (eGFR).


1. European Society of Urogenital Radiology (ESUR). ESUR guidelines on contrast agents-2018. 10.0 Disponibile alla pagina: [citato 26 aprile 2023].
2. Corbett M, Duarte A, Llewellyn A, et al. Point-of-care creatinine tests to assess kidney function for outpatients requiring contrast-enhanced CT imaging: systematic reviews and economic evaluation. Health Technol Assess 2020; 24: 1-248. doi: 10.3310/hta24390.
3. ACR Committee on Drugs and Contrast Media. ACR Manual on Contrast Media-2023. Disponibile alla pagina: [citato 26 aprile 2023].
4. Duarte A, Walker S, Altunkaya J, et al. Cost-effectiveness of point-of-care creatinine testing to assess kidney function prior to contrast-enhanced computed tomography imaging. Eur J Radiol 2021;142:109872. doi: 10.1016/j.ejrad. 2021.109872.



Attention. Please note that these items are provided only for information and are not intended as a substitute for consultation with a clinician. Patients with any specific questions about the items on this list or their individual situation should consult their clinician.