Do not request anti-TPO (anti-thyroid peroxidase) and anti-Tg (anti-thyroglobulin) antibody tests in the monitoring of autoimmune thyroid disease.
The repetition over time of anti-TPO and anti-Tg antibodies for follow-up, in case of diagnosed autoimmune thyropathy, has no clinical utility.
Anti-TPO and anti-Tg antibodies should not be sought in the case of autoimmune thyrotoxicosis / hyperthyroidism; search instead for anti-TSHR antibodies (TRAb). The research of anti-TPO is useful only in case of negativity of TRAb (possible diagnosis of non-Graves thyrotoxicosis).
In the diagnosis of hyperthyroidism, the research of anti-TPO and anti-Tg is widely requested as a first test, while the diagnostic antibody is the one directed towards the TSH receptor.
Do not diagnose Urinary Tract Infection based on urine cultures alone
Urine culture has to be performed after having a urine sample checked for the presence of leucocytes and/or nitrites, with dipstick, or by microscopic urinalysis, and in some special cases, together with urinoculture. In the absence of a pathologic multistick test or...
If throat culture is performed, susceptibility tests on isolates should not be executed in children with acute pharyngitis.
To date, streptococcal isolates are university sensitive to penicillin and amoxicillin. Susceptibility tests increase costs without providing benefits in terms of choice of antibiotic therapy.The campaign DOING MORE DOES NOT MEAN DOING BETTER – CHOOSING WISELY ITALY is promoted by Italy’s Slow Medicine
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