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Don’t ask for AST, LDH, total CK, CK-MB or myoglobin for the diagnosis of acute myocardial infarction.

Don’t ask for AST, LDH, total CK, CK-MB or myoglobin for the diagnosis of acute myocardial infarction.

by cristiano | Oct 17, 2018

The only laboratory test that really contributes to the diagnosis of acute myocardial infarction is the cardiac troponin (I or T). Especially with the more recent formulations at elevated analytical sensitivity this test presents characteristics of diagnostic...
Don’t perform serum protein electrophoresis nor search of urinary Bence-Jones protein as laboratory test before contrast media administration.

Don’t perform serum protein electrophoresis nor search of urinary Bence-Jones protein as laboratory test before contrast media administration.

by cristiano | Oct 17, 2018

The only real drawback for the administration of contrast media is renal insufficiency. It can be diagnosed measuring serum creatinine (increased) and calculating the glomerular filtration rate (eGFR). These are the only laboratory tests to perform. Patients with...
Do not perform genetic tests and assessment of sperm DNA fragmentation in all male patients with sperm abnormalities.

Do not perform genetic tests and assessment of sperm DNA fragmentation in all male patients with sperm abnormalities.

by cristiano | Oct 17, 2018

Genetic testing in patients with impaired seminal parameters and history of couple infertility must be proposed in selected cases. A wide use of such tests represents an inappropriate clinical practice both from a clinical and an economic point of view. The analysis...
Do not perform genetic tests and assessment of sperm DNA fragmentation in all male patients with sperm abnormalities.

Do not measure serum free testosterone in the suspicion of male hypogonadism.

by cristiano | Oct 17, 2018

Available immunoassays seem to underestimate testosterone levels and, they are not reliable for free testosterone measurement. The mass spectrometry and equilibrium dialysis are more accurate methodologies. However, they are laboriously, relatively expensive,...
Avoid prescribing routine immunological tests in children with recurrent respiratory infections.

Avoid prescribing routine immunological tests in children with recurrent respiratory infections.

by cristiano | Oct 17, 2018

Immunological and genetic investigations are not need when the child is suffering from undifferentiated common viral infections affecting the upper airways and when there is no family history of primary lung diseases or hereditary immunodeficiencies. The decision to...
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