by Valeria Confalonieri | Mar 13, 2023
Administration of a single i.m. dose of vitamin K within the first 6 hours of life is enough to prevent hemorrhagic disease of the newborns. If not given (e.g., due to parental refusal), oral administration must be recommended, which is less effective and should...
by Valeria Confalonieri | Mar 13, 2023
Children are physiologically born with tight foreskin at birth which appears to be intact, flexible and scarless. Separation occurs naturally over time: it resolves within 3 years of age in 90% of children, within 6 years in 92%, within 16 years in 99%. In case of...
by Valeria Confalonieri | Jan 12, 2023
The different mechanism of direct oral anticoagulants (DOACs) compared to traditional oral anticoagulant therapy explains the better risk/benefit ratio of these drugs associated with a reduction of intracranial bleeding in different clinical settings (atrial...
by Valeria Confalonieri | Aug 2, 2022
Surgical site infections (SSIs) are increasingly sustained by microorganisms resistant to several antibiotics, particularly methicillin-resistant S. aureus (MRSA) and extended-spectrum beta-lactamase- producing Enterobacteria (ESBLs). In the patient undergoing...
by Valeria Confalonieri | Aug 2, 2022
Administration of peri-operative antibiotics within 60 minutes after the start of surgery, and particularly after skin incision, appears to ensure adequate drug concentration in the serum and tissues at the site of surgery so as to reduce the risk of postoperative...
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