Don’t routinely request creatin kinase-MB (CK-MB), total creatin kinase (CK), aspartato transaminase (AST), lactic-dehydrogenase (LDH) e myoglobin diagnosing Acute Coronary Syndromes (ACS).
The cardio-specific troponins (cTn) are considered the markers of choice for the diagnosis of Myocardial Infarction (MI) and Acute Coronary Syndromes (ACS) on the basis of their specificity, sensitivity (both analytical and clinical) and negative predictive value...
Don’t perform the determination of urine glucose for the monitoring of diabetes mellitus.
Urinary glucose measurement lacks the requested diagnostic sensitivity. The test of choice for monitoring diabetic patients is glycated hemoglobin (HbA1c).
Do not use the determination of 25OH vitamin D (25OH-D) as a routine or screening test to determine the status of hypovitaminosis without a specific clinical indication.
According to documents produced by international and national regulatory bodies the measurement of 25OH-D should be reserved for: – a small number of patients with persistent symptoms of profound asthenia, myalgias, diffuse or localised bone pain suspicious for...
Do not require urinary vanillymandelic acid and plasma and/or urinary catecholamines for diagnosis of pheochromocytoma-paraganglioma.
For the diagnosis of pheochromocytoma-paraganglioma require free plasma metanephrines and, if these are not available, fractionated urinary metanephrines. The remarkable sensitivity of plasma and urinary metanephrines allows the diagnosis to be excluded when they are...The campaign DOING MORE DOES NOT MEAN DOING BETTER – CHOOSING WISELY ITALY is promoted by Italy’s Slow Medicine
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