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Don’t request blood ammonium measurement for diagnosis or management of hepatic encephalopathy (HE) in patients with chronic hepatopathy.

Don’t request blood ammonium measurement for diagnosis or management of hepatic encephalopathy (HE) in patients with chronic hepatopathy.

by Valeria Confalonieri | Dec 12, 2023

High blood ammonium alone adds no information in the diagnosis, staging, and prognosis of hepatic encephalopathy (HE) in patients with chronic hepatopathy, and ammonium concentration rarely correlates with symptoms severity and outcomes.
Don’t request blood ammonium measurement for diagnosis or management of hepatic encephalopathy (HE) in patients with chronic hepatopathy.

Don’t measure procalcitonin outside of evidence-based protocols defined by professional Societies or at the health organization/regional/national level.

by Valeria Confalonieri | Dec 12, 2023

Procalcitonin (PCT) has been proposed to discriminate infections and in, particular, bacterial sepsis from viral and other causes and to reduce antibiotic prescribing. The heterogeneity of measurement methods, adopted cut-offs and recommended protocols have greatly...
Don’t request blood ammonium measurement for diagnosis or management of hepatic encephalopathy (HE) in patients with chronic hepatopathy.

Don’t request uric acid as part of routine assessment of cardiovascular risk, obesity or diabetes.

by Valeria Confalonieri | Dec 12, 2023

The association between uric acid and the risk of major cardiovascular events and/or cardiovascular mortality has long been studied, but the cost-effectiveness of pharmacological reduction of asymptomatic hyperuricemia of this strategy in preventing cardiovascular...
Do not overlook the risk of patient colonization by multi-resistant microorganisms

Do not overlook the risk of patient colonization by multi-resistant microorganisms

by Valeria Confalonieri | Aug 2, 2022

Surgical site infections (SSIs) are increasingly sustained by microorganisms resistant to several antibiotics, particularly methicillin-resistant S. aureus (MRSA) and extended-spectrum beta-lactamase- producing Enterobacteria (ESBLs). In the patient undergoing...

Do not perform test investigating genes associated with food metabolism and food intolerances (genetic testing for nutrition) to define a dietary path

by Valeria Confalonieri | Oct 27, 2020

Many tests used for nutritional purposes are not to be considered informative as they consider only a subset of the genetic component associated with multifactorial traits, such as food intolerances and individual metabolic characteristics. The genetic tests currently...
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