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Do not perform routine laboratory tests or screenings without a clear clinical question and within an inappropriate retesting interval.

Do not perform routine laboratory tests or screenings without a clear clinical question and within an inappropriate retesting interval.

by Valeria Confalonieri | Oct 15, 2025

The issue of appropriateness in laboratory testing is central from the standpoint of environmental sustainability. Inappropriateness entails negative consequences, including interpretative errors and incidental findings leading to unnecessary interventions, increased...
Do not perform blood tests routinely and daily in patients admitted to Intensive Care, but only on the basis of specific clinical questions.

Do not perform blood tests routinely and daily in patients admitted to Intensive Care, but only on the basis of specific clinical questions.

by Valeria Confalonieri | Feb 18, 2025

Routine and systematic laboratory tests are not recommended for patients admitted to the Intensive Care Unit. It has been shown that routinely requesting them, rather than on the basis of specific clinical questions or with the aim of modifying the therapeutic plan,...
Do not perform blood tests routinely and daily in patients admitted to Intensive Care, but only on the basis of specific clinical questions.

Do not perform routine blood tests on patients undergoing surgery (or anaesthetic evaluation).

by Valeria Confalonieri | Feb 18, 2025

Routine and systematic execution of pre-operative laboratory tests is not recommended. The most recent international guidelines (NICE 2018 and ESA 2016), based on the current evidence, do not recommend their routine execution; if performed systematically they do not...
Do not prescribe periodic examinations without a specific diagnostic hypothesis.

Do not prescribe periodic examinations without a specific diagnostic hypothesis.

by Valeria Confalonieri | Dec 12, 2023

Prescribing unnecessary tests is detrimental to both patients and the ecosystem, representing a lamentable waste of resources. With the exception of the three oncological screening programs endorsed by the Italian Ministry of Health (breast cancer, cervical cancer,...
Do not perform routine laboratory tests or screenings without a clear clinical question and within an inappropriate retesting interval.

Don’t request amylase in addition to lipase if acute pancreatitis is suspected.

by Valeria Confalonieri | Dec 12, 2023

The diagnosis of acute pancreatitis is based on persistent and severe abdominal pain, high blood lipase or amylase value, and characteristic imaging. Lipase is more sensitive and specific than amylase and remains high longer.
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