Do not prescribe Vitamin K Antagonists if the patient has no contraindication to the use of direct oral anticoagulants (DOACs).
The different mechanism of direct oral anticoagulants (DOACs) compared to traditional oral anticoagulant therapy explains the better risk/benefit ratio of these drugs associated with a reduction of intracranial bleeding in different clinical settings (atrial...
Do not administer antibiotic for peri-operative prophylaxis before 60 minutes prior to surgical incision and do not continue it postoperatively unless specifically indicated
Administration of peri-operative antibiotics within 60 minutes after the start of surgery, and particularly after skin incision, appears to ensure adequate drug concentration in the serum and tissues at the site of surgery so as to reduce the risk of postoperative...
Do not perform peri-operative antibiotic prophylaxis when it is not necessary
The choice of administering peri-operative antibiotics depends on the type of surgery, the related infectious risk, and the patient’s underlying condition. The goal of proper peri-operative antibiotic prophylaxis is on the one hand to prevent morbidity and...
Do not modify, reduce, or discontinue usual therapies without a specific clinical indication in children and adolescents with chronic disease and COVID-19.
Children with chronic illnesses are a high-risk population from an infectious standpoint and, therefore, may be susceptible to developing more severe SARS-CoV-2 illness. Of relevance is the recommendation to educate children and their families about preventive...The campaign DOING MORE DOES NOT MEAN DOING BETTER – CHOOSING WISELY ITALY is promoted by Italy’s Slow Medicine
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