An oral dose of vitamin K is not recommended in term newborns who received an intramuscular shot at birth
Administration of a single i.m. dose of vitamin K within the first 6 hours of life is enough to prevent hemorrhagic disease of the newborns. If not given (e.g., due to parental refusal), oral administration must be recommended, which is less effective and should...
Do not prescribe benzodiazepines and Serotonergic Antidepressants (SSRIs) after an acute cardiovascular event without planning for a follow-up review.
Benzodiazepines (BDZ) are the most prescribed drugs in Western countries and up to 30% of patients prescribed it during hospitalization continue to take it at 12 months. BDZs are associated with a 5-fold increase in cognitive impairment, psychomotor impairment, and...
Do not prescribe Vitamin K Antagonists if the patient has no contraindication to the use of direct oral anticoagulants (DOACs).
The different mechanism of direct oral anticoagulants (DOACs) compared to traditional oral anticoagulant therapy explains the better risk/benefit ratio of these drugs associated with a reduction of intracranial bleeding in different clinical settings (atrial...
Do not administer antibiotic for peri-operative prophylaxis before 60 minutes prior to surgical incision and do not continue it postoperatively unless specifically indicated
Administration of peri-operative antibiotics within 60 minutes after the start of surgery, and particularly after skin incision, appears to ensure adequate drug concentration in the serum and tissues at the site of surgery so as to reduce the risk of postoperative...The campaign DOING MORE DOES NOT MEAN DOING BETTER – CHOOSING WISELY ITALY is promoted by Italy’s Slow Medicine
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