Don’t use fluoroquinolone antibiotics in empiric therapies, even if for severe infections, but use antibiotics with less impact on antibiotic resistance phenomenon and with less side effects.
After the amino penicillin, fluoroquinolones, and in particular levofloxacin and ciprofloxacin, are the antibiotics utilized the most in Italy. The resistance of most microorganisms to fluoroquinolones, that is constantly increasing and it is proportional to the use...
Don’t use antimicrobials to treat asymptomatic bacteriuria in older adults
The prevalence of asymptomatic bacteriuria tends to increase with age and is common in nursing home residents (up to 50% of subjects). Unnecessary antibiotic treatment for asymptomatic bacteriuria in older adults do not reduce the rates of complication and is...
Don’t routinely prescribe lipid-lowering medications in people aged 80 years and over especially for primary prevention of cardiovascular disease; don’t use statins in elderly patients with severe frailty
Given the limited high quality evidence and documented statin adverse effects (including myopathy, medication interactions and new onset diabetes) main cardiologic guidelines do not recommend statin therapy for primary prevention in people aged 80 years and over. The...
Don’t prescribe a medication without conducting a drug regimen review (medication reconciliation)
The prevalence of polypharmacy in old age (commonly defined as the use of 5 or more drugs) is on the rise in high income countries. In Italy, the proportion of people 65 years of age and older prescribed five or more medications rose from 43% to 53% between 2000 and...The campaign DOING MORE DOES NOT MEAN DOING BETTER – CHOOSING WISELY ITALY is promoted by Italy’s Slow Medicine
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