Do not measure serum cortisol and plasma corticotropin (ACTH) at random times during the day as first-line tests in suspected Cushing’s syndrome.

Do not screen asymptomatic subjects. Do not request an extended panel of thyroid function tests in suspected thyroid function impairment; limit to TSH or TSH Reflex in all cases where it is not contraindicated. Do not require FT3 determination for monitoring levothyroxine therapy in patients with hypothyroidism.

There is currently insufficient evidence to assess the benefit-harm ratio of screening for thyroid dysfunction in asymptomatic adults. Extensive panels of thyroid function tests used in hospital and, in particular, outpatient settings have been found to be less...
Do not prescribe antihistamines for preventing asthma in children.

Asthma should not be diagnosed without performing spirometry.

Spirometry is the best tool for assessing lung function in asthmatic children, and allows to define the disease severity, monitor the response to pharmacological treatment and achieve symptoms control. Patient’s history and physical examination alone, not combined...