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Don’t request amylase in addition to lipase if acute pancreatitis is suspected.

Don’t request amylase in addition to lipase if acute pancreatitis is suspected.

by Valeria Confalonieri | Dec 12, 2023

The diagnosis of acute pancreatitis is based on persistent and severe abdominal pain, high blood lipase or amylase value, and characteristic imaging. Lipase is more sensitive and specific than amylase and remains high longer.
Don’t request amylase in addition to lipase if acute pancreatitis is suspected.

Don’t request erythrocyte sedimentation rate to screen asymptomatic patients or as a general test to look for inflammatory states in patients with undiagnosed conditions.

by Valeria Confalonieri | Dec 12, 2023

C-reactive protein (CRP) is more sensitive, specific and rapid in the acute phase of inflammation. CRP should be preferred to detect both the onset and resolution of a systemic inflammatory state.
Don’t request amylase in addition to lipase if acute pancreatitis is suspected.

Don’t request uric acid as part of routine assessment of cardiovascular risk, obesity or diabetes.

by Valeria Confalonieri | Dec 12, 2023

The association between uric acid and the risk of major cardiovascular events and/or cardiovascular mortality has long been studied, but the cost-effectiveness of pharmacological reduction of asymptomatic hyperuricemia of this strategy in preventing cardiovascular...
Don’t request amylase in addition to lipase if acute pancreatitis is suspected.

Don’t request blood ammonium measurement for diagnosis or management of hepatic encephalopathy (HE) in patients with chronic hepatopathy.

by Valeria Confalonieri | Dec 12, 2023

High blood ammonium alone adds no information in the diagnosis, staging, and prognosis of hepatic encephalopathy (HE) in patients with chronic hepatopathy, and ammonium concentration rarely correlates with symptoms severity and outcomes.
Don’t request amylase in addition to lipase if acute pancreatitis is suspected.

Don’t measure procalcitonin outside of evidence-based protocols defined by professional Societies or at the health organization/regional/national level.

by Valeria Confalonieri | Dec 12, 2023

Procalcitonin (PCT) has been proposed to discriminate infections and in, particular, bacterial sepsis from viral and other causes and to reduce antibiotic prescribing. The heterogeneity of measurement methods, adopted cut-offs and recommended protocols have greatly...
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