by cristiano | Oct 17, 2018
Biosimilars are approved by regulatory agencies after demonstrating comparable safety, efficacy, and immunogenicity to the reference (originator) product. They offer benefits such as reducing drug costs, improving treatment access, and fostering innovation. However,...
by cristiano | Oct 17, 2018
Numerous scientific studies have shown, and several guidelines (NICE, WHO) recommend, that intravenous antibiotic therapy should be promptly switched to oral therapy once the IV-to-oral (IV-PO) switch criteria are met—or discontinued if no longer necessary. The...
by cristiano | Oct 17, 2018
Current evidence on continuous glucose monitoring (CGM) in type 2 diabetes is limited and of low quality. Available studies suggest only a modest improvement in HbA1c levels with CGM, without an increased risk of hypoglycemia. There is no robust evidence to support...
by cristiano | Oct 17, 2018
The clinical impact of diagnosing atrial fibrillation (AF) in asymptomatic individuals through screening programs remains not fully established, as current literature has not consistently demonstrated a reduction in thrombotic events. Furthermore, the patient...
by cristiano | Oct 17, 2018
Shared planning of care is provided for by Law 219/2017 “Rules on Informed Consent and Advance Treatment Provisions”. It allows the sick person, if desired, and the treating physician to align themselves on the goals of care, on futile or disproportionate...
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