Avoid routine use of Infective endocarditis profilaxis in mild to moderate native valve disease

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Topic Area


Despite of high frequency of bacteremia associated to dental procedures, the related risk for infective endocarditis (IE) is very low, both in general population and in cardiac patients. Extensive use of profilaxis is not supported by evidence. Profilaxis should be restricted to high risk patients (i.e. patients with worse prognosis associated to IE or at higher risk to develop an IE).


1. Prevention of Infective Endocarditis Guidelines From the American Heart Association. A Guideline From the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2007; 116: 1736-1754.
2. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009). The Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). European Heart Journal (2009) 30, 2369–2413.



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