Do not request the dosage of ENA (Extractable Nuclear Antigens) / ENA profile in patients with Raynaud’s phenomenon before having performed a capillaroscopy.
Raynaud’s phenomenon mainly affects women between 20 and 40 years of age. In a high percentage of cases ranging between 50% and 90%, this phenomenon is primitive; in such cases it is not necessary to make specific therapies, but only a symptomatic treatment and...
Do not request the dosage of ANCA (antibodies against the cytoplasm of neutrophils) only in the presence of a clinical suspicion of connectivitis, without adequate and documented evaluation or evident clinical suspect of a vasculitis.
As is well known, ANCAs are associated with a group of small vessel vasculites called ANCA-associated vasculitis, which include microscopic polyangiitis, granulomatosis with polyangiitis (M. of Wegener) and eosinophilic granulomatosis with polyangiitis (m....
Do not request the dosage of anti-CCP antibodies (cyclic citrullinated peptide) simply based on the presence of arthralgia.
On the basis of the simple presence of arthralgia, advanced diagnostic investigations are not proposed that could easily be inappropriate, and that mainly have a prognostic significance for a correct rheumatological clinical evaluation as a function of early...
Don’t routinely prescribe serum cancer markers during the diagnostic or staging procedures in cancer care.
The serum tumor markers are often required in an appropriate way as they need a simple blood sample. Given the high cost of each prescription tests and the high number of required tests it represents a considerable employment of resources; in addition it represents a...The campaign DOING MORE DOES NOT MEAN DOING BETTER – CHOOSING WISELY ITALY is promoted by Italy’s Slow Medicine
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