Don’t use antipsychotics as the first choice to treat behavioral symptoms of dementia, avoiding prescription before careful evaluation and removal of precipitating factors.
People with dementia often exhibit behavioral symptoms such as agitation, aggression, anxiety, irritability, depression, apathy and psychosis. In this context, antipsychotic medicines are often prescribed, but they often provide limited and inconsistent benefits, with...
Don’t prescribe neither chemotherapy nor radiotherapy in the treatment of ductal carcinoma in situ of the breast.
The widespread screening for early detection of breast cancer has led to the frequent identification of early forms of cancer, especially carcinoma in situ: lobular carcinoma in situ and, more frequently, ductal carcinoma in situ (DCIS). Since these types of cancer...
Don’t routinely use cancer-directed therapy for solid tumor patients with low performance status (3 or 4) or progressive after 2-3 therapeutic lines, but prioritize palliative care.
The anticancer treatments in general are likely to be ineffective in patients with solid tumors with the following characteristics: low performance status (3-4), no response to previous evidence-based therapies, not eligibility for a clinical trial, the absence of...
Don’t prescribe antibiotics to prevent infectious complications from neutropenia in cancer patients treated with standard dose chemotherapy.
The most frequent complication of chemotherapy is myelotoxicity with particular reference to the neutropenia. Neutropenia. is a serious cause of impairment of the immune system with the risk of infection, sepsis and septicemia. Normally the relevant pathogens are...The campaign DOING MORE DOES NOT MEAN DOING BETTER – CHOOSING WISELY ITALY is promoted by Italy’s Slow Medicine
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