Don’t prescribe antibiotic therapy to patients colonized by multi-resistant antibiotics microorganisms without signs of infection.

Don’t use fluoroquinolone antibiotics in empiric therapies, even if for severe infections, but use antibiotics with less impact on antibiotic resistance phenomenon and with less side effects.

After the amino penicillin, fluoroquinolones, and in particular levofloxacin and ciprofloxacin, are the antibiotics utilized the most in Italy. The resistance of most microorganisms to fluoroquinolones, that is constantly increasing and it is proportional to the use...