Prescribe fecal occult blood test (FOBT) only for screening of colorectal cancer.

Type of practice

Laboratory tests

Topic Area

Gastroenterology

FOBT is a screening test, intended for asymptomatic individuals who fall within the risk group defined by the national or regional screening program. It is not a diagnostic test and therefore should not be performed in individuals presenting with signs or symptoms suggestive of possible colon disease, such as diarrhea, overt gastrointestinal bleeding, or iron-deficiency anemia. Unfortunately, 26–51% of FOBTs are performed inappropriately, leading to an increase in unnecessary colonoscopies and a higher risk of endoscopic complications.

Sources

1. Gluskin AB, Dueker JM, Khalid A. High Rate of Inappropriate Fecal Immunochemical Testing at a Large Veterans Affairs Health Care System. Fed Pract 2021;38:270-275. doi: 10.12788/fp.0142.
2. Soin S, Akanbi O, Ahmed A, et al. Use and abuse of fecal occult blood tests: a community hospital experience. BMC Gastroenterol 2019;19:161. doi: 10.1186/s12876-019-1079-9.
3. Lee MW, Pourmorady JS, Laine L. Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: A Systematic Review and Meta-Analysis. Am J Gastroenterol 2020;115:662-670. doi: 10.14309/ajg.0000000000000495.

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Attention. Please note that these items are provided only for information and are not intended as a substitute for consultation with a clinician. Patients with any specific questions about the items on this list or their individual situation should consult their clinician.