Do not perform creatinine clearance tests in situations where it is impossible to ensure an accurate urine collection, or when it is not necessary to measure urinary creatinine excretion. In such cases, it is preferable to assess renal function by calculating the eGFR (the volume of the filtrate).

Do not perform creatinine clearance tests in situations where it is impossible to ensure an accurate urine collection, or when it is not necessary to measure urinary creatinine excretion. In such cases, it is preferable to assess renal function by calculating the eGFR (the volume of the filtrate).

by | Oct 17, 2018

Clearance (or the volume of plasma from which a given substance – creatinine in the case in point – is completely removed per unit of time) is measured using a mathematical formula comprising four factors: blood creatinine concentration; urinary creatinine...
Asthma should not be diagnosed without performing spirometry.

Asthma should not be diagnosed without performing spirometry.

by | Oct 17, 2018

Spirometry is the best tool for assessing lung function in asthmatic children, and allows to define the disease severity, monitor the response to pharmacological treatment and achieve symptoms control. Patient’s history and physical examination alone, not combined...
Asthma should not be diagnosed without performing spirometry.

Do not use salmeterol in children with acute asthma.

by | Oct 17, 2018

In children with acute asthma, long-acting beta2-agonists (LABAs) are not recommended, because of slow onset of action (10-20 minutes). Clinical data on safety in children are really limited. Moreover, in children with acute asthma salmeterol monotherapy increases the...