Don’t request erythrocyte sedimentation rate to screen asymptomatic patients or as a general test to look for inflammatory states in patients with undiagnosed conditions.

Don’t request erythrocyte sedimentation rate to screen asymptomatic patients or as a general test to look for inflammatory states in patients with undiagnosed conditions.

Type of practice

Laboratory tests

Age

Adult, Geriatric, Pediatric

Topic Area

Laboratory Medicine

C-reactive protein (CRP) is more sensitive, specific and rapid in the acute phase of inflammation. CRP should be preferred to detect both the onset and resolution of a systemic inflammatory state.

Sources

1. Kratz A, Plebani M, Peng M, et al.ICSH recommendations for modified and alternate methods measuring the erythrocyte sedimentation rate. Int J Lab Hematol 2017; 39:448-457. doi: 10.1111/ijlh.12693.
2. Bartlett KJ, Vo AP, Rueckert J, et al. Promoting appropriate utilisation of laboratory tests for inflammation at an academic medical centre. BMJ Open Qual 2020;9:e000788.
3. Lapić I, Padoan A, Bozzato D, et al. Erythrocyte Sedimentation Rate and C-Reactive Protein in Acute Inflammation. Am J Clin Pathol 2020;153:14-29. doi: 10.1093/ajcp/aqz142. PMID: 31598629.
4. Harrison M. Erythrocyte sedimentation rate and C-reactive protein. Aust Prescr 2015;38:93-4.

Download

PDF

Attention. Please note that these items are provided only for information and are not intended as a substitute for consultation with a clinician. Patients with any specific questions about the items on this list or their individual situation should consult their clinician.