In patients with type 2 diabetes being treated with drugs which do not cause hypoglycemia, once the glycemic objective has been reached and the results of self- monitoring become fairly predictable, daily monitoring of the glycemia does not add information for maintaining glycemic control, and sometimes can cause anxiety. There are many exceptions like, for example, use for educational purposes, acute illnesses that can recur,worsening of glycemic compensation, the use of hypoglycemizing drugs, when self- monitoring is often indispensable from time to time in order to achieve set goals.