Don’t perform PET/CT with [18F]FDG (Fluorodeoxyglucose) in suspected peripheral osteomyelitis and in differential diagnosing between acute and chronic infection.

Type of practice


Topic Area

Nuclear Medicine

Since [18F] FDG-PET/CT showed high sensibility in the diagnosis of spondylitis and spondylodiscitis, some Nuclear Medicine physicians may substitute scintigraphy with labelled white blood cell with this technique in every infectious disease. Labelled white blood cell represent however the gold standard nuclear medicine imaging for acute infection-inflammation diagnosis.


1. Gemmel F et al Prosthetic joint infections: radionuclide state-of-the-art imaging. Eur J Nucl Med Mol Imaging 2012; 39: 892-909.
2. Gemmel F et al Radionuclide imaging of spinal infections. Eur J Nucl Med Mol Imaging 2006; 33: 1226-37.
3. Prandini N et al Nuclear medicine imaging of bone infections. Nucl Med Commun 2006 Aug; 27: 633-44.

Attention. Please note that these items are provided only for information and are not intended as a substitute for consultation with a clinician. Patients with any specific questions about the items on this list or their individual situation should consult their clinician.