Do not perform population screening for 25OH vitamin D deficiency.

Type of practice

Laboratory tests

The Endocrine Society Guidelines recommend screening in individuals at risk of deficiency and not for assessing the health of the general population, as there is no evidence of its efficacy in terms of health outcomes. Despite the high prevalence of deficiency / insufficiency reported in the literature, awareness and supplementation programs in adults and children are considered more effective than screening.The Endocrine Society recommends the monitoring of 25OH-D levels in subjects at risk of deficiency and in osteoporosis assessment or functional diagnosis of proximal myopathies.


1. Holick MF, Binkley NC, Bischoff-Ferrari HA et al (2011) Evaluation, Treatment and Prevention of vitamin D deficiency: an Endocrine Society Clinical Practice guideline. J Clin Endocrinol Metab; 96: 1911-30.
2. Holick MF (2010) The D-lemma: to screen or not to screen for 25OH vitamin D concentrations. Clin Chem 56: 729-731.
3. LeBlanc ES, Zakher B, Monica Daeges M, et al (2015) Screening for Vitamin D Deficiency: A Systematic Review for the U.S. Preventive Services Task Force 162: 109-122.
4. LeFevre ML (2015) US Preventive Services Task Force. Screening for vitamin D deficiency in adults: US Preventive Services Task Force recommendation statement. Ann Intern Med 162: 133-140.

Attention. Please note that these items are provided only for information and are not intended as a substitute for consultation with a clinician. Patients with any specific questions about the items on this list or their individual situation should consult their clinician.