Avoid contraindicating routinely vaccination in case of allergies.

Type of practice

Other treatments

Topic Area


A history of allergies or mild allergic reactions are not contraindications to vaccination. Local and mild systemic reactions (redness of the injection site and/or fever) after vaccination reactions are common and do not contraindicate the administration of doses of vaccine in the future. Special precautions should be followed only in the case of persons who have presented serious systemic reactions with risk of life (severe dyspnea, stridor, cyanosis, mental status changes, hypotension). The presence of sensitization to egg protein is not a contraindication to vaccination against measles, mumps and rubella.


1. Kelso JM, Greenhawt MJ, Li JT, Nicklas RA, et al: Adverse reactions to vaccines practice parameter 2012 update. J Allergy Clin Immunol 2012 Jul; 130(1): 25-43.
2. Santuccio C, Trotta F: Rapporto Agenzia Italiana del Farmaco, 2013. http://www.agenziafarmaco.gov.it/it/content/relatori-aifa
3. Gallo G, Mel R, Rota MCl: Rapporti ISTISAN 09/13. http://www.salute.gov.it/imgs/C_17_pubblicazioni_1947_allegato.pdf
4. Kelso JM, Greenhawt MJ, Li JT: Joint Task Force on Practice Parameters (JTFPP). Update on influenza vaccination of egg allergic patients .Ann Allergy Asthma Immunol. 2013 Oct; 111(4): 301-2.

Attention. Please note that these items are provided only for information and are not intended as a substitute for consultation with a clinician. Patients with any specific questions about the items on this list or their individual situation should consult their clinician.