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Don’t perform genetic tests for monogenic diseases without specific indication both in the physiological procreation or by assisted reproduction technology (ART).

Don’t perform genetic tests for monogenic diseases without specific indication both in the physiological procreation or by assisted reproduction technology (ART).

by cristiano | Oct 17, 2018

Only in the case where the geneticist recognizes a reproductive risk for a specific monogenic disease, the genetic test for that single disease should be performed on the component at risk. Whether a monogenic autosomal recessive disease is present, the test should be...
Don’t perform genetic tests for monogenic diseases without specific indication both in the physiological procreation or by assisted reproduction technology (ART).

Don’t perform genetic tests directly to consumers, purchased on websites, pharmacies, gyms, beauty institutions, without a doctor’s prescription.

by cristiano | Oct 17, 2018

The public may be misled about the real benefit of these tests and it is often not aware of the limitations of the test. Without consulting a geneticist is also difficult to interpret correctly the test result. Finally, it is found that those who undergo the tests...
Don’t perform genetic tests for monogenic diseases without specific indication both in the physiological procreation or by assisted reproduction technology (ART).

Don’t perform genetic testing for mutations analysis in the 5,10-Methylene TetraHydrofolate Reductase (MTHFR) gene

by cristiano | Oct 17, 2018

Since the risk of developing thrombotic events is conferred by the presence of hyperhomocysteinemia, it is considered more useful and valid, from the clinically point of view, consider the value of plasma homocysteine, which is also influenced by several other...
Don’t use bevacizumab for its various oncologic indications.

Don’t use bevacizumab for its various oncologic indications.

by cristiano | Oct 17, 2018

Based on the most recent literature assessing the effectiveness of bevacizumab, the benefit expected from this agent for its various oncologic indications is in the order of a few weeks of survival gained. Since the cost of bevacizumab is high and its incremental...
Don’t use bevacizumab for its various oncologic indications.

Don’t prefer bioresorbable coronary stents over traditional drug-eluting stents.

by cristiano | Oct 17, 2018

The recent development of bioresorbable coronary stents (Bioresorbable Vascular Scaffolds, BVS) represent a promising therapeutic option as compared with traditional drug-eluting stents (DES). However, based on the most recent evidence currently available, BVS (the...
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