The top five recommendation list for students on diagnostic and therapeutic appropriateness has been drafted by Italian Medical Students’ Association (SISM). A task force composed of five medical students has developed a list of seventeen recommendations based on experiences gathered during their studies. This list was shared with italian medical students through an online form. They were asked to give each recommendation a grade from 1 to 5. A total of 635 students from all the Italian medicine and surgery universities has answered the form, which was then used by the task force to choose the five final recommendations.