{"id":2871,"date":"2018-10-17T19:07:50","date_gmt":"2018-10-17T17:07:50","guid":{"rendered":"https:\/\/choosingwiselyitaly.org\/raccomandazione-prof\/do-not-use-phytoestrogens-for-menopausal-related-sexual-symptoms\/"},"modified":"2019-10-01T15:51:42","modified_gmt":"2019-10-01T13:51:42","slug":"do-not-use-phytoestrogens-for-menopausal-related-sexual-symptoms","status":"publish","type":"raccomandazione-prof","link":"https:\/\/choosingwiselyitaly.org\/en\/raccomandazione-prof\/do-not-use-phytoestrogens-for-menopausal-related-sexual-symptoms\/","title":{"rendered":"Do not use phytoestrogens for menopausal-related sexual symptoms."},"content":{"rendered":"<p>There is no strong scientific evidence for the use of phytoestrogens in the treatment of menopausal-related sexual symptoms (e.g. hypoactive sexual desire disorder, excitement disorder, orgasmic disorder, dyspareunia, vaginismus) and\/or hot flushes. Biological actions of these molecules can be affected by: multiple action sites, relative number of subtypes of receptors, different distribution among target tissues of functional co-activators and co-repressors, potential non-genomic action of estrogens even in cells without specific receptors. Phytoestrogens have the same general contraindications of on-label estrogen compounds.<\/p>\n","protected":false},"featured_media":2387,"template":"","meta":{"_edit_lock":["1569937776:5"],"_edit_last":["5"],"_wpml_media_duplicate":["0"],"_wpml_media_featured":["0"],"_thumbnail_id":["2387"],"_wpml_word_count":["{\"total\":219,\"to_translate\":{\"it\":219}}"],"_yoast_wpseo_primary_eta":[""],"_yoast_wpseo_primary_disciplina":["119"],"_yoast_wpseo_primary_tipologia":[""],"wpcf-pacchetto":["SIAMS #1"],"wpcf-bibliografia":["1. Worsley R, Santoro N, Miller KK, Parish SJ, Davis SR. 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