{"id":2812,"date":"2018-10-17T19:06:18","date_gmt":"2018-10-17T17:06:18","guid":{"rendered":"https:\/\/choosingwiselyitaly.org\/raccomandazione-prof\/do-not-request-the-dosage-of-anti-ccp-antibodies-cyclic-citrullinated-peptide-simply-based-on-the-presence-of-arthralgia\/"},"modified":"2019-10-02T12:30:31","modified_gmt":"2019-10-02T10:30:31","slug":"do-not-request-the-dosage-of-anti-ccp-antibodies-cyclic-citrullinated-peptide-simply-based-on-the-presence-of-arthralgia","status":"publish","type":"raccomandazione-prof","link":"https:\/\/choosingwiselyitaly.org\/en\/raccomandazione-prof\/do-not-request-the-dosage-of-anti-ccp-antibodies-cyclic-citrullinated-peptide-simply-based-on-the-presence-of-arthralgia\/","title":{"rendered":"Do not request the dosage of anti-CCP antibodies (cyclic citrullinated peptide) simply based on the presence of arthralgia."},"content":{"rendered":"<p>On the basis of the simple presence of arthralgia, advanced diagnostic investigations are not proposed that could easily be inappropriate, and that mainly have a prognostic significance for a correct rheumatological clinical evaluation as a function of early aggressive therapy. Therefore, the request of these anti-CCP antibodies should be carried out only in the case of rheumatological evaluation which induces the prescription.<\/p>\n","protected":false},"featured_media":3065,"template":"","meta":{"_edit_lock":["1570012234:5"],"_edit_last":["5"],"_wpml_media_duplicate":["0"],"_wpml_media_featured":["0"],"_yst_prominent_words_version":["1"],"_thumbnail_id":["3065"],"_wpml_word_count":["{\"total\":223,\"to_translate\":{\"it\":223}}"],"_yoast_wpseo_primary_eta":[""],"_yoast_wpseo_primary_disciplina":["114"],"_yoast_wpseo_primary_tipologia":[""],"wpcf-pacchetto":["CReI #1"],"wpcf-bibliografia":["1. Kuru O, Bilgici A, Birinci A, Ulusoy H, Durupinar B. Prognostic value of anti-cyclic citrullinated peptide antibodies and rheumatoid factor in patients with rheumatoid arthritis. Bratisl Lek Listy 2009; 110(10): 650.\r\n2. van Jaarsveld CH, ter Borg EJ, Jacobs JW, Schellekens GA, Gmelig-Meyling FH, van Booma-Frankfort C, de Jong BA, van Venrooij WJ, Bijlsma JW. The prognostic value of the antiperinuclear factor, anti-citrullinated peptide antibodies and rheumatoid factor in early rheumatoid arthritis. Clin Exp Rheumatol 1999 Nov-Dec; 17(6): 689-97.\r\n3. D. Aletaha and S.Bl\u00fcm. Therapeutic implications of autoantibodies in rheumatoid arthritis  RMD Open. 2016 May 17; 2(1): e000009. doi: 10.1136\/rmdopen-2014-000009. eCollection 2016."],"wpcf-posizione-prof":["1"],"wpcf-collegare":["N"],"wpcf-link-intercheck-prof":["N"],"wpcf-area-ordinamento":["Rheumatology"],"_yoast_wpseo_content_score":["90"],"_yoast_wpseo_focuskeywords":["[]"],"_yoast_wpseo_keywordsynonyms":["[\"\"]"],"_wpml_location_migration_done":["1"],"_layouts_template":["layout-for-raccomandazioni-professionista"],"_wp_page_template":["default"],"_et_dynamic_cached_shortcodes":["a:4:{i:0;s:13:\"et_pb_section\";i:1;s:9:\"et_pb_row\";i:2;s:12:\"et_pb_column\";i:50;s:10:\"et_pb_text\";}"],"_et_dynamic_cached_attributes":["a:0:{}"],"et_enqueued_post_fonts":["a:3:{s:6:\"family\";a:1:{s:15:\"et-gf-work-sans\";s:136:\"Work+Sans:100,200,300,regular,500,600,700,800,900,100italic,200italic,300italic,italic,500italic,600italic,700italic,800italic,900italic\";}s:6:\"subset\";a:2:{i:0;s:5:\"latin\";i:1;s:9:\"latin-ext\";}s:9:\"cache_key\";s:75:\"{\"gph\":-1,\"divi\":\"4.27.6\",\"wp\":\"6.8.5\",\"enable_all_character_sets\":\"false\"}\";}"]},"eta":[{"term_id":96,"name":"Adult","slug":"adult","term_group":0,"term_taxonomy_id":96,"taxonomy":"eta","description":"","parent":0,"count":272,"filter":"raw"}],"disciplina":[114],"tipologia":"Laboratory tests","class_list":["post-2812","raccomandazione-prof","type-raccomandazione-prof","status-publish","has-post-thumbnail","hentry","eta-adult","disciplina-rheumatology","tipologia-laboratory-tests"],"_links":{"self":[{"href":"https:\/\/choosingwiselyitaly.org\/en\/wp-json\/wp\/v2\/raccomandazione-prof\/2812","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/choosingwiselyitaly.org\/en\/wp-json\/wp\/v2\/raccomandazione-prof"}],"about":[{"href":"https:\/\/choosingwiselyitaly.org\/en\/wp-json\/wp\/v2\/types\/raccomandazione-prof"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/choosingwiselyitaly.org\/en\/wp-json\/wp\/v2\/media\/3065"}],"wp:attachment":[{"href":"https:\/\/choosingwiselyitaly.org\/en\/wp-json\/wp\/v2\/media?parent=2812"}],"wp:term":[{"taxonomy":"eta","embeddable":true,"href":"https:\/\/choosingwiselyitaly.org\/en\/wp-json\/wp\/v2\/eta?post=2812"},{"taxonomy":"disciplina","embeddable":true,"href":"https:\/\/choosingwiselyitaly.org\/en\/wp-json\/wp\/v2\/disciplina?post=2812"},{"taxonomy":"tipologia","embeddable":true,"href":"https:\/\/choosingwiselyitaly.org\/en\/wp-json\/wp\/v2\/tipologia?post=2812"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}